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:: Volume 10, Issue 4 (winter 2010) ::
J Ardabil Univ Med Sci 2010, 10(4): 303-309 Back to browse issues page
Assessment of the Level of copper in serum and 24-hour urine in pre-eclamptic pregnant women
Fatemeh Ranjkesh , Shokouhosadat Abotorabi, Jamileh Kajinebaf, Fereshteh Abbasi
Abstract:   (4157 Views)

 Background & objectives: Pre-eclampsia, as a idiopathic disease, is one of the most important causes of maternal and fetal morbidity and mortality throughout the world. Deficient or excessive level of trace elements can be considered as an unfavorable factor in pregnancy.The aim of this study was to evaluate copper status in pre-eclamptic women .

 Methods: 95 pre-eclamptic and 92 healthy pregnant women were enrolled in a case - control study .The sera and 24-hour urine copper of two groups were measured by atomic absorption spectrometry. The data were recorded and analyzed statistically by using t-test, X2, and pearson's correlation .

 Result: Copper concentration of serum and 24-hour urine in pre-eclamptic patients were significantly higher than normotensive ones (p<0.000). Intensity of pre-eclampsia did not correlate with copper concentration in the serum and 24-hour urine .

 Conclusions: The results suggest that the high level of copper in maternal serum and urine is in correlation with pre-eclampsia but pre-eclampsia intensity have not significant effects on copper levels. However, further studies would be helpful for this test to be used as a prognostic method for pre-eclampsia.

Keywords: Serum copper; 24-hour urine copper; Pre-eclampsia
Full-Text [PDF 202 kb]   (1576 Downloads)    
Type of Study: article | Subject: Special
Received: 2010/09/20 | Accepted: 2011/01/20 | Published: 2011/02/28
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Ranjkesh F, Abotorabi S, kajinebaf J, Abbasi F. Assessment of the Level of copper in serum and 24-hour urine in pre-eclamptic pregnant women. J Ardabil Univ Med Sci. 2010; 10 (4) :303-309
URL: http://jarums.arums.ac.ir/article-1-201-en.html


Volume 10, Issue 4 (winter 2010) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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