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:: Volume 13, Issue 3 (autumn 2013) ::
J Ardabil Univ Med Sci 2013, 13(3): 317-326 Back to browse issues page
The Relationship between Leptin and Growth Hormones with Anthropometric Indices and Blood Glucose Levels in Healthy Men
Homeira Nasiri Rineh , Ferangis Khanpour
Abstract:   (5504 Views)

  Background & Objectives: Obesity is an important risk factor for many diseases and hormonal and metabolic factors have a great impact on its development. The aim of this study was to investigate the relationship between leptin and growth hormones with anthropometric indices and blood glucose in healthy men.

  Methods: This study is a cross-sectional study on 30 healthy adult men aged 18-49 years in Tonekabone city during 2011-2012. Samples were randomly selected and information on anthropometric parameters (waist circumference, body mass index and waist/hip ratio), fasting blood sugar, serum levels of leptin and growth hormones were recorded and blood sampling was performed After 12 hours of fasting (at 8 am). Data were analyzed using software SPSS 15 by non- parametric Mann – Whitney and Spearman test s and multiple regression analysis.

  Results: Serum leptin levels were negatively correlated with serum level of growth hormone ( P<0.05) and positively related to body mass index ( P<0.01) , waist circumference ( P<0.01) and the body weight ( P<0.05). Inverse relationship between serum growth hormone levels with age and fasting blood glucose were observed (P<0.05). Serum levels of leptin were significantly higher in overweight and obese than normal weight subjects (P<0.01) and mean leptin levels in subjects with central obesity ( waist circumference≥94cm) were significantly higher than men without central obesity (waist circumference<94cm) (P<0.01).

  Conclusion: This study showed that growth hormone level was negatively correlated with serum level of leptin. Low serum growth hormone and high serum leptin levels were associated with obesity and upper body fat distribution. Obesity and abdominal obesity are also associated with increased risk of metabolic syndrome

Keywords: Leptin; Growth Hormone; Anthropometric Parameters; Fasting Blood Sugar
Full-Text [PDF 160 kb]   (1750 Downloads)    
Type of Study: article | Subject: Special
Received: 2013/01/14 | Accepted: 2013/06/18 | Published: 2013/09/23
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Nasiri Rineh H, Khanpour F. The Relationship between Leptin and Growth Hormones with Anthropometric Indices and Blood Glucose Levels in Healthy Men. J Ardabil Univ Med Sci. 2013; 13 (3) :317-326
URL: http://jarums.arums.ac.ir/article-1-108-en.html


Volume 13, Issue 3 (autumn 2013) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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